Title Postdoctoral Research Associate I (Multiple Positions)
Department Chemistry & Biochemistry - Sci (2536)
Location Main Campus
The Tomasiak lab in the Department of Chemistry and Biochemistry at the University of Arizona seeks to bridge cutting edge structural biology to medically relevant drug and nutrient transporters. Recent advances in electron microscopy and membrane protein biochemistry (especially lipid stabilization and directed evolution) have transformed membrane protein structural biology. The lab seeks a motivated researcher interested in these areas and with expertise in:
- Structural biology (x-ray crystallography and/or cryo-EM) and biophysics
- Membrane protein function
- Drug design
- Deep sequencing functional assays
Candidates with one or more of these skills who also want to learn the other areas are highly encouraged to apply. You will lead an investigation the structure/function relationships in exciting, medically relevant targets and have the potential opportunity to interface with several laboratories as well as the pharmaceutical industry. Applicants must have or will soon have a Ph.D. in biochemistry, pharmacology, or a related field.
The lab is situated in the picturesque city of Tucson. Tucson was designated a World City of Gastronomy by UNESCO in 2015 and 2nd best small city by National Geographic/Resonance Consulting with its outstanding nightlife, food, hundreds of miles of beautiful outdoor hiking and an affordable cost of living. The University of Arizona has a long history in optics and measurement science, ranking in the top 10 in both analytical chemistry Atomic/Molecular/Optical physics by US News and World Report.
The Department of Chemistry & Biochemistry (CBC) is a university-wide department with faculty and staff in both the College of Science and the College of Medicine. This unique organizational structure provides synergistic opportunities for faculty and students who are pursuing their educational and research goals across the broad range of subdisciplines represented in CBC. Moreover, CBC offers 10 undergraduate and graduate degrees in either Chemistry (BS, BA, MA, MS, PhD) or Biochemistry (BS, BA, MA, MS, PhD), as a result of the merger of the former Biochemistry Department with the Chemistry Department in 2009. Explore our website to find out more about CBC@UA!
Outstanding UA benefits include health, dental, vision, and life insurance; paid vacation, sick leave, and holidays; UA/ASU/NAU tuition reduction for the employee and qualified family members; access to UA recreation and cultural activities; and more!
The University of Arizona has been listed by Forbes as one of America’s Best Employers in the United States and WorldatWork and the Arizona Department of Health Services have recognized us for our innovative work-life programs.
Duties & Responsibilities
Establishing a membrane protein structural biology project.
Design and implementation of membrane protein growth and purification protocols.
Structural determination of an integral membrane protein or associated proteins in drug resistance, nutrient transport, hormone transport (can include transcription factors, signaling proteins, accessory proteins).
Present and publish findings to the scientific community.
Knowledge, Skills, & Abilities
Required to have or will have Ph.D. in a field related to Biochemistry by desired start date.
Experience with cloning, construct design, and cell culture.
Experience with protein purification using IMAC, size exclusion chromatography.
Demonstrated success with first author publications.
Ability to guide a project independently.
Demonstrated ability to communicate scientific findings.
Experience with membrane protein purification.
Experience with cryo-electron microscopy.
Experience with large data sets and high throughput sequencing/mutagenesis.
Full Time/Part Time Full Time
Number of Hours Worked per Week 40
Job Category Postdoctoral Research
Benefits Eligible Yes - Full Benefits
Posted Rate of Pay DOE
Type of criminal background check required: Name-based criminal background check (non-security sensitive)
Posting Detail Information
Posting Number P20564
Number of Vacancies Multiple
Desired Start Date 07/02/2018
Position End Date (if temporary)
Limited to Current UA Employees No
Open Date 05/18/2018
Open Until Filled Yes
Review Begins On 05/28/2018