Postdoctoral Research Associate in Memphis, TN

St. Jude Children's Research Hospital   •  

Memphis, TN 38101

Industry: Hospitals & Medical Centers


Not Specified years

Posted 55 days ago

We are seeking a highly motivated and ambitious postdoctoral fellow to join the group of Dr. Giedre Krenciute. The lab is located in the Department of Bone Marrow Transplantation and Cellular Therapy at St. Jude Children's Research Hospital in Memphis, TN. We use genetically engineered T cells to design novel and safe therapeutic approaches for pediatric brain tumors.

Projects include:

  • Designing, generating and optimizing CAR T cells to target pediatric brain tumor associated antigens
  • Enhancing CAR T cell effector function using different genetic manipulations
  • Studying tumor microenvironment and its effect on CAR T cell function

Interested applicants should send their CV, a cover letter describing research experience and interests, and names and email addresses of three references to:

Minimum Experience

In addition to a Ph.D., the candidate should have expertise in the following techniques (all highly preferred but not required):

  • Cloning (Ligation cloning, any iteration of Gibson Assembly (InFusion, NEBuilder, etc));
  • DNA related work (propagation in bacteria, isolation, PCR);
  • RNA related work (isolation, qPCR)
  • Tissue culture
  • Flow cytometry
  • WB
  • Transfection, transduction and transformation.
  • Plasmid design using SnapGene (or equivalent software)

Training in brain tumor research, immunology and/or CAR T cell biology is preferred but not required.

Valid Through: 2019-11-12