The Staff Scientist or Research Associate will be responsible for managing the mass spectrometry lab, under the direction of Dr. Schilling. Work will include discussions with collaborators, recommendations on experimental design, and operation of mass spectrometric instrumentation, quality control and troubleshooting when necessary. Subsequent data analysis and data processing will lead to the generation of results reports. This collaborative position is at the interface of Buck Institute scientists with the mass spectrometry and Schilling labs. This position offers an opportunity to interact with cutting-edge technologies in liquid chromatography-mass spectrometry, while also working with a large variety of collaborative biological projects in a premier research setting.
- Advise on experimental design and discussions with collaborators and Buck Institute investigators specific to the research projects.
- Operate mass spectrometric instrumentation.
- Interact closely with Schilling lab members and other MS Core personnel.
- Analyze and process statistical data, and generate results reports.
- Prepare graphical representations of experimental data.
- Perform some Proteolytic digestions and solid-phase extraction, in coordination with lab research associates.
- Execute immunoprecipitation of peptides and proteins.
- Maintain and QC MS laboratory equipment including HPLC etc.
- Develop new proteomics workflows as needed for projects.
- PhD in Biology, Chemistry or other related fields; possibly BA/BS or MS with additional relevant experience
- 2+ years of laboratory experience in a mass spectrometry / proteomics lab
- Familiar with mass spectrometry instrumentation
- Demonstrated experience operating MS instruments independently
- Ability to troubleshoot LC-MS/MS problems and optimize instrument performance
- Strong organizational skills and the ability to multitask
- Attention to detail and execution of work protocols in a reproducible fashion
- Excellent analytical and critical thinking skills
- Proficiency with computers required, i.e. Microsoft Office and scientific software for processing of mass spectrometry experiments