Coordinates with principal investigators and directs the R&D activities of technical staff focused on organoid technology development and applications. This role works closely with the Core Director and staff to offer expert support for experimental design, sample preparation, and data generation to support the research and therapeutic development of Weill Cornell Medicine and surrounding science community.
Further, this role provides cutting-edge resources that enable critical advances in basic and translational research and offer high-end technologies and devotes oneself to translational and basic research areas in regenerative medicine, vascular biology, stem cell biology, cancer, cardiovascular disease, lung diseases, metabolic diseases, neurodegenerative diseases, children's health, global health, and infectious diseases.
Will consider academic appointments as Assistant Professor of Medicine
- Manages day-to-day operations of Core services and products to be provided, which includes the distribution of normal human organoids derived from the biopsy or autopsy tissues from multiple organ systems and mouse organoids derived from mouse tissues.
- Oversees on-demand services of CRISPR-Cas9 mediated genomic engineering of organoids, distribution of human organoid derivation, and assembly/distribution of organ-on-chip for modeling multiple-tissue interactions and custom organoid chip design/assembly.
- Oversees imaging service, integrated bioinformatics service to support organoid research, individual service consultation, training, and support and education for students, postdocs, and investigators interested.
- Develops, manages and reports against service timelines. Adjusts service schedule with input from the directors and relevant core organizer.
- Leads the ongoing review of work products to ensure the quality of key service deliverables consistent with product standards.
- Coordinates the development and submission of requisite regulatory documents, including IRB and ESCRO submission, to achieve overall research goals.
- Monitors progress against service and prepares/presents operation and Unit information proactively to directors and staff internally.
- Implements a communications plan for the service status and reports to address uers’ requirements. Organizes and documents meetings with PI’s and staff and presentations to senior management.
- Focuses and coordinates the service to assure the planned timeline.
- Participates, as appropriate, in internal and external audits.
Minimum of four (4) years of laboratory experience.
Extensive experience with cell cultures is a must, and sufficient supervisory experience or equivalent.
Broad knowledge in regulatory affairs and operations management.
Experience in microscopy and flow cytometry instrumentation.
Proficient knowledge in Biology/Cell Biology and Medical Technology.
Knowledge, Skills and Abilities
- Demonstrated proficiency with MS Office Suite and database applications.
- Strong communication skills.
- Ability to review service outputs for opportunities to accelerate service completion and enhance proposed service outcomes.
- Ability to work cooperatively and effectively with others to set goals, resolve problems, and make decisions that enhance organizational effectiveness.
- Demonstrated ability to positively influence others to achieve results that are in the best interest of the organization.
- Ability to assess situations to determine the importance, urgency, and risks, and make clear and timely decisions.
- Ability to set priorities, develop a work schedule, monitor progress towards goals, and track details/data/information/activities.
- Ability to determine strategies to move the organization forward, set goals, create and implement action plans, and evaluate the process and results.
- Ability to assess problem situations to identify causes, gather and process relevant information, generate possible solutions, and make recommendations and resolve the problem.
Licenses and Certifications
Working Conditions/Physical Demands
Ability to work safely in a BSL2 environment.
Work will be in both in a laboratory and an office environment, but the purpose of the service may sometimes take incumbent to non-standard workplaces.
This is a day shift position with hours Monday-Friday 8 am-5 pm, but may be required to work some evenings and weekends to meet service deadlines.