Director, Translational Development and Diagnostics - Hematology / Multiple Myeloma

Celgene   •  

Summit, NJ

Industry: Pharmaceuticals & Biotech

  •  

11 - 15 years

Posted 40 days ago

Responsibilities

  • Leads a group of translational scientists as a group lead and leads the translational development of portfolio of compounds translational annual goals and objectives for the myeloma group (for internal /external, translational collaboration, compound specific plans etc), ORQs, and is accountable for their progress monitoring in association with TD scientists 
  • Assists in developing and maintaining group budget and workforce plan 
  • Represents Translational Development in cross-functional project and strategy teams 
  • Interfaces with commercial including early commercialization group and Medical Affairs to provide scientific support for cross-functional TD goals and support IIT studies 
  • Manages and supervises preclinical collaboration strategy across the pipeline compounds for clinical assets 
  • Assists in managing key strategic and/or collaborative projects along with TD scientists 
  • Supports regulatory submissions, regulatory interactions, writes/reviews translational sections for regulatory response and answers to regulatory queries for the TD group 
  • Interfaces with the diagnostic group for projects that need diagnostics development 
  • Communicates regularly and prepares and makes presentations within the department and externally as required
  • Works with lab head to integrate translational research in the Summit lab of Celgene. 

Requirements

  • PhD or MD with at least 12 years of relevant work experience, including a minimum of 10 years of experience in drug development in an industry setting
  • Track record in large and small companies, leading innovative efforts to deploy technologies and assays for enhanced translational capabilities
  • Excellent communication, managerial and scientific qualities are expected
  • Ability to interact effectively across boundaries using influencing and relationship building skills.
  • Competence in analysis and solving of problems, and the ability to prioritize and make tradeoffs to achieve goals.

Technical Skills
 

  • In-depth understanding of multiple myeloma, clinical landscape, evolving therapy, competitive scenario
  • Strong understanding of clinical, translational and mechanistic data of myeloma therapies in NDMM and RRMM settings 
  • Good understanding of drug development process in an industry setting
  • Strong background in clinical biomarker discovery and analysis, research tools, platforms and assays  
  • Understanding of late-stage drug and translational development process
  • Proven ability to work with disease teams/experts to develop strategies to support development and life cycle management efforts tailored to regional markets (i.e, US, EU, CAN)
  • Strong verbal and written communication skills with experience in developing written documents such as primary manuscripts/publications/reviews, disease strategies, mechanism slides, regulatory submissions, strategic communications, literature/market/pt segment analyses 
  • Proven scientific/project leadership expertise (working in teams, managing collaborations, people/projects)
  • Ability to synthesize complex scientific and business problems into strategy and tactics
  • Basic understanding of IP, contracting terms and provisions  

Other Attributes
 

  • A problem solver who creatively and knowledgeably transcends departmental function to act as a resource to entire research effort and senior managers in development. 
  • Identifies issues early and proposes innovative solutions.
  • Communicates within the larger organization and external community.
  • Provides expert guidance to multi-disciplinary teams and senior management.
  • A leader whose scope of influence stretches across Celgene.
  • A leader who influences external scientific community.

  • Req #: 17001552