Director/Sr. Director, Pathology, Genentech Research

Genentech   •  

San Francisco, CA

Industry: Business Services


15+ years

Posted 395 days ago

The incumbent will carry out his or her responsibilities at Genentech's campus in South San Francisco, CA. He or she will report to Dr. Morgan Sheng, Vice President, Neuroscience, within the Genentech Research organization. The Head of Research Pathology is responsible for the objectives, strategy and implementation of all Research Pathology efforts that support lab scientists engaged in drug discovery within Genentech's Research organization. The Department Head is also responsible for ensuring that high quality pathology support is provided to laboratory and clinical scientists engaged in biomarker strategy/development/deployment across the drug development pipeline. These latter activities are carried out within the Genentech Development organization and can extend into "late stage" clinical development efforts (Phase III clinical trials). The Research Pathology department provides Research and Development personnel with intellectual and technical expertise concerning pathology-related study design, tissue selection, microscopic interpretation, analytical techniques, and support for regulatory and clinical queries. The Pathologists' collaborative support of R and D scientists include histopathology interpretive expertise informed by traditional diagnostic categories and by detailed and current understanding of molecular and cellular biology. These activities include provision of cutting edge technology platforms for analysis of fresh, frozen and formalin-fixed paraffin embedded tissues an cell lines used to assess (i) new therapeutic targets and pathways and (ii) biomarkers relevant to diagnosing and treating human disease. The Department is comprised of 11 highly trained, board-certified pathologists who collaborate directly with investigators and oversee all pathology support activities. The Department also manages 6 core pathology laboratories that include necropsy, clinical pathology, histopathology, immunohistochemistry/ in situ hybridization, a human tissue biorepository, and advanced light microscopy, electron microscopy and digital pathology. The Department Head will be responsible for leading and developing the more than 65 internal and external staff, including the group of 11 Pathologists and more than 50 pathology laboratory staff. This is a highly impactful role, responsible for creating, managing and coordinating the intellectual and technical aspects of pathology support responsibilities that (i) are deployed across Genentech's three major therapeutic discovery/development areas (oncology, immunology, neuroscience), (ii) span both of Genentech's major R and D functions (Research and Development), (iii) extend to support for some "late stage"/Phase III clinical trials activities, and (iv) are carried out cross-functionally with other research and discovery teams at Genentech.

Who You Are

Qualified candidates will meet the following requirements:

  • The candidate must have:
    • an earned M.D. or D.V.M., or the direct equivalent earned in ex-U.S. countries.
    • scientific training that could include formal Ph.D. degree training and/or lab-based post-doctoral fellowship(s)
    • completed a residency in Anatomic and/or Clinical Pathology
    • Pathology Board Certification (ABP, ACVP, as relevant to the degree)
  • The ideal candidate will be an internationally recognized leader in the field of pathology, with a minimum 15years of progressive and successful experience in the field of pathology and/or fields directly related to pathology, as evidenced by:
    • achieving positions of increasing managerial and strategic leadership responsibilities at his/her home institution and in national and international organizations.
    • a successful track record of leading teams or groups that provide pathology expertise to laboratory and/or clinical scientists in complex, multidisciplinary environments, encompassing individuals with a diversity of skills and backgrounds.
    • a strong record of basic and/or translational research, preferably with a focus on human disease, in areas that could include biomarker discovery and utilization, pathology informatics, or basic mechanisms of human disease, accompanied by multiple publications in top tier journals, presentations at international meetings, and service on scientific strategy and review panels.
  • The ideal candidate will have a proven ability to successfully lead, recruit and cultivate a high achieving organization that attracts, develops, motivates and retains world class talent, and an ability to keep the organization focused on achieving well-defined objectives within established timelines.
  • The ideal candidate will have outstanding leadership capabilities beyond his or her own organization, with demonstrated skill in building, guiding and motivating effective teams, and fostering productive research collaborations, working effectively with lab scientists, clinical scientists, R&D leaders and executives to advance R&D projects. The ideal candidate will have a well-developed positive attitude toward ambiguity, and unexpected changes, given that these can characterize any complex organization including those engaged in drug discovery environment.
  • The candidate must have an outstanding ability to be clear and concise in oral and written communications. He/she will also have outstanding partnering skills, with the ability and willingness to seek and provide information with transparency among key stakeholders. The idea candidate will have demonstrated experience in developing/presenting to cross-functional nonclinical and clinical advisory boards.
  • For candidates seeking to include research efforts as part of their responsibilities, a well-developed research plan is required, with an outstanding scientific track record and an active and productive research program.

Job ID: 2565500122