Director, RWE Internal Medicine Scientist

ROLE SUMMARY

The Real World Evidence (RWE) group is part of the Evidence Generation Platform within Global Medical Affairs. This growing group develops and implements integrated, end-to-end, RWE generation plans based on stakeholder needs. Key stakeholders include Commercial Strategy and Innovation, Global Access and Value, Global Medical Affairs, Global Medical Epidemiology, Global Product Development, Global Regulatory Science, and Worldwide Research, Development and Medical.

The Internal Medicine (IM) therapeutic area (TA) is responsible for delivering medicines that make a real difference in the quality of life for patients with cardiovascular and metabolic disease (CVD), the number one cause of death worldwide. Additionally, the IM pipeline and in-line assets include biologics, small molecules and nucleic acid therapies to treat cachexia, anorexia, type 2 diabetes, obesity, non-alcoholic steatohepatitis, uterine fibroids, venous thromboembolism, and other related conditions.

The RWE Scientist/Director will use their knowledge of RWE to determine how it can support a product throughout its lifecycle, from molecule to marketplace. The RWE Scientist/Director will deliver timely real world insights (RWI) and RWE in collaboration with cross-functional teams, provide guidance on appropriate sources of real world data and methods for meeting request objectives, and will create easy-to-understand summary reports. The RWE Scientist/Director will lead the development and execution of noninterventional study protocols in accordance with all applicable standard operating procedures and other relevant policies.

The RWE Scientist/Director will work closely with the IM RWE Lead on developing strategic roadmaps with cross-functional teams and use tactical plans to identify key RWE external data partnership opportunities. They will oversee data procurement activities (e.g., landscape assessments and due diligence or supporting contract development for external studies). They will act as a mentor / advisor to other RWE Scientists, directing their work.

ROLE RESPONSIBILITIES

• Interact with cross-functional IM product, asset, and indication teams to identify opportunities for RWE to answer important and relevant research questions
• Recommend appropriate use of RWE throughout development lifecycle
• Coordinate projects and resources related to RWE across teams, including Early Clinical Development, Global Product Development franchise / asset teams, Medical Affairs, Health Economics and Outcomes Research, Commercial, Global Medical Epidemiology, and others
• Assess feasibility of answering research questions using available sources of RWD using both rapid analytic platforms (eg, Aetion, Panalgo) and traditional statistical programming (eg, SAS, R, SQL)
• Develop research questions into analytical plans by clarifying objectives, methods, and desired output
• Collaborate with RWD programmers to execute analytical plans, review and troubleshoot statistical programming, interpret draft findings, refine and finalize approach
• Create scientifically rigorous RWE study protocols that comply with internal SOPs and external best practices
• Lead cross-functional teams conducting RWE studies
• Contribute to development of RWE evidence generation plans
• Communicate interim findings from RWE analyses and studies to cross-functional teams; incorporate team feedback into ongoing analyses
• Provide daily direction, mentorship, motivation, and oversight of more junior RWE resources in their RWE Scientist Team, & direct them to co-develop of business rules, standards (eg for disease / cohort definitions), methods and SOPs with cross-functional colleagues
• Document all requests and track progress toward project completion, create and measure ROI metrics, and ensure support to achieve business goals

BASIC QUALIFICATIONS

Candidate demonstrates a breadth of diverse leadership experiences and capabilities including: the ability to influence and collaborate with peers, develop and coach others, oversee and guide the work of other colleagues to achieve meaningful outcomes and create business impact.

• 8+ (with a master's degree) , 10+ (Bachelor's degree) years' experience with a proven successful track record of scientific analysis for Non-Interventional Studies, healthcare analytics, RWE generation, other research studies or clinical quality improvement studies, with specific experience with a range of real world data such as EHR, medical or pharmacy claims, patient registries, or other data sources
• Ability to independently develop research questions into scientifically rigorous and feasible analytical plans based on best available RWD sources, including explanation of pros/cons for different sources
• Deep subject matter expertise on commonly used sources of RWD, including claims databases, Electronic Health Records, registries, patient participating research networks and other sources
• Ability to critically evaluate analytic results against the literature, subject matter expert feedback or other reliable sources to ensure biological and medical credibility in alignment with cross-functional team strategy / priorities
• Strong experience in communicating in verbal and written form with all levels of personnel with diverse backgrounds, and able to create and deliver clear presentations to teams
• Quality focused and well organized
• Experience working under pressure with a high level of autonomy and internal motivation and adapting rapidly within evolving digital environment
• Ability to mentor junior team members, helping to establish a culture of team-work and collaboration
• Ability to develop statistical programs (ie, SAS, R, SQL) to explore patient counts, health care utilization, treatment patterns, and other common RWE questions in claims, EHR, and other data sources
• Ability to query rapid analytical platforms (eg, IHD, Aetion)
• Ability to rapidly learn new domains to understand the latest scientific or medical findings and incorporate them into projects as appropriate; to interpret data dictionaries and other technical documentation

PREFERRED QUALIFICATIONS

• The ideal candidate will have 10+ years experience in RWE analytics within the biopharmaceutical or healthcare consulting industries; a Master's degree in Health/Nursing /Biomedical Informatics, Public Health, HEOR, Epidemiology, Biostatistics/Statistics, or Other Biological Science fields with a substantial quantitative and computational component, or other related fields; or commensurate professional experience,
• Proven track record of peer-reviewed scientific publications (eg, abstracts, posters, manuscripts) related to RWE
• Experience working in cardiovascular, metabolic, or other TAs related to IM (eg, women's health, migraine)
• Strong ability to manage teams in a highly-matrixed environment, with demonstrated excellence in team-work and collaboration highly desired
• Knowledge of efficient programming practices and the software development life cycle preferred

In addition, Seeking candidates with the following skillsets:

• Project Management: experience in overseeing a program of multiple projects in a cross-matrix environment, including tracking milestones and metrics, with a history of leading or acting as a major player in real world data-related projects to coordinate colleagues and drive teams to achieve goals
• Training / Education: experience in leading training and educational sessions on RWE
• Experience conducting analyses to support assumptions related to business development activities (eg, market sizing, due diligence, commercial forecasts)
• Knowledge of common sources of RWD outside the US

Other Job Details:

Last Date to Apply for Job: August 25th, 2023

Additional Location Information: US remote

Eligible for Relocation Package: No

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The annual base salary for this position ranges from $156,900.00 to $261,500.00. In addition, this position offers an annual bonus with a target of 20.0% of the base salary and eligibility to participate in our share based long term incentive program. Benefits offered include a retirement savings plan, paid vacation, holiday and personal days, paid caregiver/parental and medical leave, and health benefits to include medical, prescription drug, dental and vision coverage in accordance with the terms and conditions of the applicable plans. Pfizer compensation structures and benefit packages are aligned locally, the US Salary range provided does not apply to the Tampa, FL or any EXUS locations.

Relocation assistance may be available based on business needs and/or eligibility.

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Market Access

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