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Director, Medicinal Chemistry in Madison, WI

Arrowhead Research

Madison, WI 53703
5w ago


Physical Sciences, Life Sciences


11 - 15 years

Job Description

The Position

The Director, Medicinal Chemistry will be a key member of the drug discovery team at Arrowhead's Madison, WI-based Research and Development facility and will lead multiple internal and/or partnered drug discovery programs based on the company's RNAi-based platform technology. The candidate will contribute to overall drug discovery strategy and pipeline prioritization and will drive medicinal chemistry strategy. Significant experience with structure-based drug design, research project management and tract record of developing candidates to enter the clinic is desired.


  • Provide scientific leadership, from a medicinal chemistry perspective
  • Supervise a small team of synthetic chemists
  • Establish new drug discovery targets and projects
  • Lead internal and external discovery projects to help achieve departmental and site-wide milestone and goals
  • Provide expert insight into targeting ligands
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Valid through: 2020-3-4

About Arrowhead Pharmaceuticals

Arrowhead Research is a publicly traded (NASDAQ: ARWR) pharmaceutical company that is a component of the NASDAQ Biotechnology Index. As of 2016[update], it has no marketed products. Products in development are RNA therapeutics acting through RNA interference mechanisms of action. The company focuses on treatments for Hepatitis B, and Carcinomare. The company has six products in its pipeline, in various stages of clinical development. In 2015, the company substantially expanded its intellectual property holdings through complete acquisition of the full RNAi research and development portfolio and assets from Novartis.
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