Summary of Major Responsibilities
The Clinical Curation Scientist will work within a team of clinical professionals to perform genomics knowledge mining and content derivation supporting Exact Sciences' precision medicine platform. The Clinical Curation Scientist will collaborate with genomics and clinical teams to develop and implement an interpretive genomics guided therapy report that is informative and clinically relevant. Essential Duties and Responsibilities
Include, but are not limited to, the following:
- Contribute to our precision medicine knowledgebase by identifying, interpreting, and documenting key findings from the literature to capture gene alterations associated with drug sensitivity and resistance.
- Participate in the interpretation and analysis of identified variants from clinical samples.
- Collaborate with scientists and clinicians to refine content and structure reports.
- Contribute to additional projects in support of our broader precision medicine efforts.
- Interact effectively with bioinformaticians to develop and refine innovative strategies.
- Strong verbal and written communication skills; ability to explain concepts to a diverse audience.
- Ability to work independently on multiple tasks and perform careful, detail-oriented work within a team environment.
- Uphold company mission and values through accountability, innovation, integrity, quality, and teamwork.
- Support and comply with the company's Quality Management System policies and procedures.
- Regular and reliable attendance.
- Ph.D. or M.D. in Human Genetics, Molecular Genetics, Genomics, Cancer Biology, Molecular Biology, Pharmacology, or related field; or Master's degree in Human Genetics, Molecular Genetics, Genomics, Cancer Biology, Molecular Biology, Pharmacology, or related field and 2 years of related experience as outlined in the essential duties in lieu of Ph.D. or M.D.
- 4+ years of experience with genomic medicine and translational cancer research to include working with next-generation sequencing data.
- 4+ years of experience using public databases, tools, and resources, such as NCBI, EBI, UCSC, IGV.
- Expertise in genomic variant curation.
- Demonstrated understanding of cancer genomics, signal transduction pathways, cancer cell biology, targeted therapeutics, and whole genome, exome, and/or RNA-sequencing.
- Demonstrated ability to critically evaluate and interpret scientific literature.
- Proven record of scientific achievement as demonstrated by presentations and publications in peer-reviewed journals.
- Demonstrated ability to perform the Essential Duties of the position with or without accommodation.
- Authorization to work in the United States without sponsorship.
- Demonstrated proficiency with databases tracking the different variants and mutations.
- Experience using Bioinformatics scripting.
- Familiarity with a Linux environment.
We are an equal employment opportunity employer. All qualified applicants will receive consideration for employment without regard to age, color, creed, disability, gender identity, national origin, protected veteran status, race, religion, sex, sexual orientation, and any other status protected by applicable local, state or federal law. Applicable portions of the Company's affirmative action program are available to any applicant or employee for inspection upon request.