Antibody Engineer

Chai Discovery, Inc

$100K — $150K *
Pharmaceuticals & Biotech
5 - 7 years of experience
Job Overview by Ladders

Qualifications

  • PhD or equivalent experience in Biological Sciences, Protein Engineering, Biochemistry, or related field.
  • Experience with characterization of antibody-based biologics.
  • Proven ability to manage CRO relationships and oversee experimental design.
  • Strong background in protein engineering and molecular biology techniques.
  • Deep understanding of antibody biology and molecular engineering technologies.
  • Experience with antibody characterization methods (e.g., SPR, BLI, ELISA, flow cytometry).
  • Ability to manage multiple external collaborations effectively.

Responsibilities

  • Design and develop traditional and next-generation biologics including monoclonal and bispecific antibodies.
  • Collaborate extensively with CROs on research and development projects.
  • Oversee experimental design and ensure scientific rigor in data interpretation.
  • Guide therapeutic candidates from initial concept through to preclinical validation.
  • Contribute to the development of engineered cytokines, multifunctional antibodies, and ADCs.

Benefits

  • Cutting-edge research environment with advanced technologies.
  • Opportunities for collaboration with leading experts in the field.
  • Potential for professional growth and development in therapeutic areas.
Full Job Description
Position Overview:The Antibody Engineer will design and assist in the development of both traditional and next-generation biologics, including monoclonal antibodies, bispecific antibodies, T-cell engagers (TCEs), engineered cytokines, multifunctional antibodies, and antibody-drug conjugates (ADC) / degrader-antibody conjugates (DAC). This role involves extensive collaboration with CROs, oversight of experimental design, data interpretation, and guiding therapeutic candidates from conceptualization to preclinical validation.

Qualifications:
  • PhD or equivalent work experience in Biological Sciences, Protein Engineering, Biochemistry, or a related field.
  • Experience characterizing antibody-based biologics
  • Strong record in managing CRO relationships and experimental design.
  • Strong background in protein engineering, molecular biology techniques and/or structural biology
  • Deep understanding of antibody biology, molecular engineering, and related technologies.
  • Experience in antibody characterization methods (e.g., SPR, BLI, ELISA, flow cytometry).
  • Ability to manage multiple external collaborations effectively.

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