Scientist - Protein Purification & Biophysical Characterization
Seeking an experienced Protein Purification Scientist to utilize cutting edge downstream product technologies to develop immune tolerance technologies into targeted autoimmune disease therapeutics.
The team will produce and characterize lead molecules and collaborate with external manufacturing organizations to scale up polymers and antibody like proteins production for GMP clinical trials.
*** Design and develop recombinant molecules in various expression systems and polymeric chemical entities.
*** Implement purification protocols on expressed molecules.
*** Train and mentor junior scientists.
*** Develop protocols, production operating procedure manuals, and similar.
*** Create, optimize, troubleshoot, modify, qualify, validate, and transfer production methods to Contract Research and Manufacturing organizations.
*** Validate biochemical assays and analytical methods for in-process characterization.
***Support formulation, drug product development, and stability studies.
*** PhD in Chemical Engineering, Biochemistry, Chemistry, or similar field.
***5+ years of Method Development and Protein Products testing experience.
***Experience with chemical modification of proteins and glycoprotein molecules.
*** Hands on knowledge of liquid chromatography (on 10+L scale) and scalable separations techniques (Ultrafiltration, Tangential Flow Filtration, Depth Filtration, or similar).
*** Familiarity with High Performance Liquid Chromatography and Immunoassays (ELISA or similar).
Join a well funded and innovative organization offering an industry competitive compensation package, bonuses, tuition reimbursement, full medical benefits, 401(k) retirement plan, life and disability insurance, career development opportunities, comprehensive vacation policy, and more!
Please reference #37645178 when responding.Education Requirements: Bachelor DegreeMinimum Experience Requirements: 5-10 yearsJob City Location: NewarkJob State Location: DEJob Country Location: USASalary Range: $80,000 to $135,000
WE ARE AN EQUAL OPPORTUNITY EMPLOYER and our employment decisions are made without regard to race, color, religion, age, sex, national origin, handicap, disability or marital status. We reasonably accommodate individuals with handicaps, disabilities and bona fide religious beliefs. Jobs Career Position Hiring. CONSIDERED EXPERIENCE INCLUDES: Top 10 Job Site Top 10 Careers Site Protein Purification Characterization Optimization Biochemist Scientist Associate Scientist Bench Scientist Chromatography Ion Exchange Hydrophobic Interaction Size Exclusion Affinity Isothermal Titration Calorimetry Surface Plasmon Resonance Analytical Size Exclusion Chromatography SDS PAGE Differential Scanning Calorimetry Circular Dichroism
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