Scientist - Protein Purification & Biophysical Characterization

Confidential Company  •  Newark, DE

5 - 7 years experience  •  Business Services

$80K - $135K
Posted on 11/23/17 by Christopher Moreno
Confidential Company
Newark, DE
5 - 7 years experience
Business Services
$80K - $135K
Posted on 11/23/17 Christopher Moreno

Seeking an experienced Protein Purification Scientist to utilize cutting edge downstream product technologies to develop immune tolerance technologies into targeted autoimmune disease therapeutics. 


The team will produce and characterize lead molecules and collaborate with external manufacturing organizations to scale up polymers and antibody like proteins production for GMP clinical trials. 




*** Design and develop recombinant molecules in various expression systems and polymeric chemical entities. 


*** Implement purification protocols on expressed molecules. 


*** Train and mentor junior scientists. 


*** Develop protocols, production operating procedure manuals, and similar.


*** Create, optimize, troubleshoot, modify, qualify, validate, and transfer production methods to Contract Research and Manufacturing organizations.


*** Validate biochemical assays and analytical methods for in-process characterization. 


***Support formulation, drug product development, and stability studies. 


Experience Sought: 


*** PhD in Chemical Engineering, Biochemistry, Chemistry, or similar field. 


***5+ years of Method Development and Protein Products testing experience. 


***Experience with chemical modification of proteins and glycoprotein molecules. 


*** Hands on knowledge of liquid chromatography (on 10+L scale) and scalable separations techniques (Ultrafiltration, Tangential Flow Filtration, Depth Filtration, or similar). 


*** Familiarity with High Performance Liquid Chromatography and Immunoassays (ELISA or similar). 


Join a well funded and innovative organization offering an industry competitive compensation package, bonuses, tuition reimbursement, full medical benefits, 401(k) retirement plan, life and disability insurance, career development opportunities, comprehensive vacation policy, and more! 


Please reference #37645178 when responding.Education Requirements: Bachelor DegreeMinimum Experience Requirements: 5-10 yearsJob City Location: NewarkJob State Location: DEJob Country Location: USASalary Range: $80,000 to $135,000


WE ARE AN EQUAL OPPORTUNITY EMPLOYER and our employment decisions are made without regard to race, color, religion, age, sex, national origin, handicap, disability or marital status. We reasonably accommodate individuals with handicaps, disabilities and bona fide religious beliefs. Jobs Career Position Hiring. CONSIDERED EXPERIENCE INCLUDES: Top 10 Job Site Top 10 Careers Site  Protein Purification Characterization Optimization Biochemist Scientist Associate Scientist Bench Scientist Chromatography Ion Exchange Hydrophobic Interaction Size Exclusion Affinity Isothermal Titration Calorimetry Surface Plasmon Resonance Analytical Size Exclusion Chromatography SDS PAGE Differential Scanning Calorimetry Circular Dichroism


DISCLAIMER: We will make every effort to consider applications for all available positions and shall use one or more of the contact methods and addresses indicated in resume or online application. Indicated location may be proximate or may be desirable point of embarkation for paid or unpaid relocation to another venue. Job descriptions may fit single or multiple presently available or anticipated positions and are NOT an offer of employment or contract implied or otherwise. Described compensation is not definite nor precise and may be estimated and approximate and is negotiable depending on market conditions and candidate availability and other factors and is solely at the discretion of employers. Linguistics used herein may use First Person Singular and First Person Plural grammatical person construction for and with the meaning of Third Person Singular and Third Person Plural references. We reserves the right to amend and change responsibilities to meet business and organizational needs as necessary. Response to a specific posting or advertisement may result in consideration for other opportunities and not necessarily the incentive or basis of the response. Nothing herein is or may be considered a promise, guarantee, offer, pledge, agreement, contract, or oath.


 If you submit an application or resume which contains your email address, we will use that email address to communicate with you about this and other positions. We use an email quality control service to maintain security and a remove and dead address filter.

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