Coordination of university major gifts activity within an assigned geographic region of the United States and responsible for personal engagement of approximately 250 key capital gifts prospects. Visit goals are established on an annual basis.
The position is for an actively funded NIH grant in cancer imaging. The successful candidate will be a member of a highly interdisciplinary lab including biologists, engineers, and imaging scientists to develop and validate advanced imaging techniques in a context of a co-clinical (preclinical and clinical) trial.
The aim of the research is to obtain better estimates of radiological properties of tissues to improve brachytherapy and proton therapy planning. These estimates will be based in part on dual energy computed tomography (DECT) measurements, with images reconstructed using a statistical iterative reconstruction technique.
Expected that the selected applicant will be involved in the design and execution of experiments to tackle the project objectives, general tasks related to the lab work routine, active participation in periodic laboratory meetings, manuscript preparation and publishing, and the presentation of work in international conferences.
Generate hypotheses based on data and literature, design and execute well-controlled experiments. The general expectation is that the candidate will be able to lead a project independently and generate publishable data.
Genetically engineered mouse models and organoids to study these processes, including traditional Cre-Lox conditional/tissue-specific mutagenesis approaches and next generation genome editing tools, with a specific focus on CRISPR/Cas site-specific nucleases and the Piggybac DNA transposon. The development of new GEMMs will be accomplished using standard techniques (molecular cloning, recombineering, pro-nuclear injection, homologous recombination), Piggybac, and CRISPR/Cas.
Potential research projects include understanding how the Hippo pathway regulates branching morphogenesis in the mouse kidney, and how Fat cadherins control planar polarity and the Hippo pathway in flies and mice.