Medicis Pharmaceutical was a medical cosmetics company founded in 1988 with headquarters in Scottsdale, Arizona. It was acquired by Valeant Pharmaceuticals in 2012 and in 2013, the company moved its headquarters to Bridgewater, New Jersey. Among their products are Solodyn and Ziana for treating acne, and Restylane and Dysport for treating facial wrinkles. Medicis was founded in 1988 by Jonah Shacknai and John Holaday. The company held its IPO in 1990, and launched its first products over the next year. In December 1997, Medicis acquired GenDerm Corporation, a dermatology pharmaceuticals company, for $60M in cash. Medicis also acquired Ucyclyd Pharma, a Baltimore-based private company, for $23.4 million in cash in April 1999. Ucyclyds main product was Buphenyl (sodium phenylbutyrate), used for treating urea cycle disorders. In 2005, they rejected a $2.2 billion unsolicited takeover proposal by Mentor.