Synygys first three clients were the pharmaceutical companies Schering-Plough, Janssen Pharmaceutica, and Wyeth-Ayerst. During its 25 years in business, Synygy served nearly all industries, including Life Sciences, Manufacturing and Distribution, Retail, Banking, Financial Services, Telecommunications, High-Tech, and Insurance (Health, Life, Property & Casualty). Synygy targeted companies with complex challenges related to sales data integration and transformation, sales incentive compensation management, quota and objectives setting, territory management, sales workflow process automation, and sales business intelligence and analytics. The company did not sell to governments or smaller companies. Synygy competed with professional services companies that include Accenture, CallidusCloud, Alexander Group, Aon Hewitt, Bain & Company, Better Sales Comp, Boston Consulting Group, Buck, Canidium, Colletti-Fiss, Cygnal Group, Deloitte, KPMG, McKinsey & Company, Mercer, OpenSymmetry, Optymyze, Sibson, Towers Watson, Valitus, and ZS Associates.