The work, expected to encompass a two-year tenure with a possible extension, will conduct mechanistic investigation of the proteins of the cardiac sarcomere, performing functional and quantitative characterization, assessment of stability, as well as protein-protein interactions.
The successful candidate will be managing a group of talented scientists in the Research Biology Department and will hold a senior-level leadership role guiding target identification, target validation and drug discovery within the research organization.
Work with discovery teams to evaluate synthetic routes and test alternatives that facilitate scale up of both target compounds and building blocks while providing insights for selection of development candidates.
Supports the clinical sub-team by providing standards for Data Capture and safety data, assessing the overall quality of data and identifying and escalating key data issues, trends or patterns that may pose overall study compliance and/or data quality concerns, e.g., frequency of queries and protocol deviations.
Plan and manage GCP and GLP compliance audits (international and domestic), including clinical investigator sites, contract clinical laboratories and CROs; to determine compliance status and identify compliance risks.
This position will report to the Head of Project Management and will act as a strategic partner with the Project Team Leader/s and all functional-area leaders to ensure efficient project planning, budgeting, prioritization and execution of strategic project goals.