GenScript

GenScript

Employees:
1,300
Market Cap:
$17.2 billion
Revenue:
$115 million
Net Income:
$200 million

GenScript

Employees:
1,300
Market Cap:
$17.2 billion
Revenue:
$115 million
Net Income:
$200 million
  • Oct 31 at 9:32 AM
    Happy Halloween everyone! GenScriptMake Research Easy! http://ow.ly/MufG30gf9uQ
  • Oct 30 at 1:00 PM
    Upgraded! Antibody Sequencing Services at GenScript: http://ow.ly/uNzs30gd4TB. Our ISO9001 certified antibody sequencing service is your reliable choice to speed up and facilitate therapeutic antibody leads discovery and development.
  • Oct 25 at 1:24 AM
    Gene Circuit Switches to Improve Combinatorial Cancer Immunotherapy: http://ow.ly/53O130g5cbe. In order to improve immunotherapy efficacy and reduce its off-target side effect, a team led by Dr Timothy Lu at MIT developed a novel gene circuit controlling expression of multiple immunomodulatory genes that regulate the immune response at multiple levels. Because this circuit requires two cancer-specific signals to be present before the response, it stimulates the immune system to target tumors more accurately and more efficiently than existing immunotherapy. The in vivo assay demonstrated that it triggers robust anti-tumor responses and increased mouse survival.
  • Oct 24 at 1:14 AM
    ZATT Protein Repairs DNA Damage Caused by Cancer Treatment: http://ow.ly/rr8r30g5biZ. NIH researchers uncovered for the first time the underlying mechanism behind cellular recovery after severe DNA damage induced by chemotherapy. A few anti-cancer drugs are known to trap the topoisomerase 2 (TOP2)-DNA complex (TOP2cc), which is an intermediate in TOP2 processing of DNA topology. This in turn conceals the TOP2-induced DNA cut, and results in the accumulation of DNA damage and cell death. In this study, it was revealed that ZATT, a SUMO ligase, could repair such DNA damages by promoting the removal of TOP2cc through a ZATT-Tyrosyl DNA phosphodiesterase 2-catalyzed and SUMO2-modulated pathway. This finding is useful in developing not only new drugs to lower tumor adaptation to chemotherapy, but also more effective chemotherapeutic drugs.

Oct 31, 9:32 AM

Happy Halloween everyone! GenScriptMake Research Easy! http://ow.ly/MufG30gf9uQ

Oct 30, 1:00 PM

Upgraded! Antibody Sequencing Services at GenScript: http://ow.ly/uNzs30gd4TB. Our ISO9001 certified antibody sequencing service is your reliable choice to speed up and facilitate therapeutic antibody leads discovery and development.

Oct 25, 1:24 AM

Gene Circuit Switches to Improve Combinatorial Cancer Immunotherapy: http://ow.ly/53O130g5cbe. In order to improve immunotherapy efficacy and reduce its off-target side effect, a team led by Dr Timothy Lu at MIT developed a novel gene circuit controlling expression of multiple immunomodulatory genes that regulate the immune response at multiple levels. Because this circuit requires two cancer-specific signals to be present before the response, it stimulates the immune system to target tumors more accurately and more efficiently than existing immunotherapy. The in vivo assay demonstrated that it triggers robust anti-tumor responses and increased mouse survival.

Oct 24, 1:14 AM

ZATT Protein Repairs DNA Damage Caused by Cancer Treatment: http://ow.ly/rr8r30g5biZ. NIH researchers uncovered for the first time the underlying mechanism behind cellular recovery after severe DNA damage induced by chemotherapy. A few anti-cancer drugs are known to trap the topoisomerase 2 (TOP2)-DNA complex (TOP2cc), which is an intermediate in TOP2 processing of DNA topology. This in turn conceals the TOP2-induced DNA cut, and results in the accumulation of DNA damage and cell death. In this study, it was revealed that ZATT, a SUMO ligase, could repair such DNA damages by promoting the removal of TOP2cc through a ZATT-Tyrosyl DNA phosphodiesterase 2-catalyzed and SUMO2-modulated pathway. This finding is useful in developing not only new drugs to lower tumor adaptation to chemotherapy, but also more effective chemotherapeutic drugs.

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