The Boston Public Health Commission, the oldest health department in the United States, is an independent public agency providing a wide range of health services and programs. It is governed by a seven-member board of health appointed by the Mayor of Boston. Its mission is to "protect, preserve, and promote the health and well-being of all Boston residents, particularly those who are most vulnerable." The commission is headquartered at 1010 Massachusetts Avenue in Boston. In 1799, The Boston Board of Health was established to combat any potential cholera outbreaks. Paul Revere was Bostons first health commissioner. In 1864 the Boston City Hospital opened, managed by the board.