In this role, the selected candidate must have a direct experience in determining the success of cell transfection using techniques such as reporter gene assays, protein analysis (western blot), real-time qPCR for mRNA quantitation, enzymatic assays, etc.
Leverage technical and analytical expertise to explore and examine data from multiple disparate sources with the goal of discovering patterns and previously hidden insights, which in turn can provide a competitive advantage or address a pressing business problem.
Work within an interdisciplinary team of molecular and computational biologists to integrate, interpret, and mine high-throughput immune phenotyping, genomics, and therapeutic response data from pre-clinical experiments and clinical samples for novel io targets, combination opportunities, and biomarkers of response.
Conduct usability assessments of websites and mobile apps with heuristics, best practices and accessibility guidelines. Conduct client workshops for research requirements, proto-personas, and use cases.
The Structural and Chemical Biology Department is seeking an experienced and highly motivated cell biologist to help drive our drug discovery efforts. The Senior Scientist would be responsible for developing robust cell based assays to investigate protein degradation through the ubiquitin proteasome system.
Develop and apply leading-edge computational analysis and biological interpretation approaches to leverage internal, public and partner datasets and empower data-driven decisions across compound development programs.
This position is key to scientific research and developing, updating and maintaining assessment tools, for all KF lines of business, from Search to Leadership and Talent Consulting, to Recruitment Process Outsourcing (Futurestep).
This position is responsible for supporting clinical development of vaccine programs by qualifying clinical assays fit-for-use for assessment of immune responses in phase 1/2 clinical trials, and also for the conduct of cell-based assays on samples acquired as part of early-stage clinical trials.
Support all scientific aspects of clinical trial(s) and program level activities as assigned, providing scientific expertise to study protocols, case report forms, statistical analysis plans, interpretation of results, clinical study reports, graphical displays.
The focus will be on cellular and animal models of fatty liver disease, inflammation and fibrosis, including signaling pathways, transcriptional regulation and disease pathway modification with Intercepts therapeutic approaches.
Responsible for the maintenance of the electronic Trial Master Files (TMF). Performs ongoing reviews of TMF to assure quality of the documentation files and compliance with Xencor SOPs, GCP and ICH Guidelines.