The role is in support of products and process development for biotherapeutics and vaccines, including antibodies, antibody-drug conjugates, and therapeutic proteins, in late-stage clinical development. The candidate will work across analytical functions, projects, and global sites.
Successful candidates will be strategic, self-motivated, creative, efficient, and will have superior organizational and detail skills. This individual must have an interest in recruiting and research and have the ability to manage multiple projects and deadlines.
The chosen candidate will be responsible for process development, scale-up, technology transfer, establishing and optimizing commercial manufacturing processes for compounding and filling of solids, soft-chews, non-sterile liquids and sterile inject (aseptic manufacturing) platforms, as well as collaborating and partnering with Manufacturing, Engineering, and Quality organizations.
In this role, the selected candidate will prepare chemically modified proteins and antibodies for a variety of down-stream assay needs; design, execute, and interpret experimental results with some supervision.
Develop the health services research program. Facilitates and independently conducts academic/clinical research, supports research utilization in nursing/clinical practice and develops an ongoing strategic plan for academic/clinical research.
In this role, the selected candidate will require track record in piezoelectric dispensing of proteins from borosilicate glass capillaries onto substrate for protein biochip fabrication, I.e. printing immobilized protein macroarrays on substrates.
A highly motivated candidate is sought for a fellowship to conduct research on the pathogenesis of congenital heart diseases in the lab of Prof. Pirooz Eghtesady, MD, PhD, Division of Pediatric Cardiovascular Surgery, Department of Surgery at Washington University School of Medicine, St. Louis, MO.
Standard molecular biology techniques such as molecular cloning, PCR, qRT-PCR, handling of retroviruses and lentiviruses, preparation and extraction of genomic DNA, RNA, Western blots, immunoprecipitation, in vitro binding assays, and ELISA.
Apply technical and analytical expertise to explore and examine data from multiple disparate sources with the goal of discovering patterns and previously hidden insights, providing a competitive advantage or addressing a pressing business problem.