The Successful candidate will become part of a creative and flexible team that will investigate host/pathogen interactions, the influence of the microbiome on host immunity and immune responses to novel vaccines with the ultimate goal of delivering novel therapeutics to address significant unmet medical need in infectious disease as well as broader indications.
The successful candidate will be able to design cell-based experiments using genetic and pharmacological manipulation of pathways and proteins in relevant cell systems to characterize molecular mode of action of tool molecules.
In this role, you will be responsible for
expression, purification, characterization, crystallization, structure determination and biophysical characterization of proteins and protein-ligand complexes.
In this role, you will be responsible to perform site monitoring visits in accordance with the study monitoring plan to ensure compliance with the investigational plan, monitoring plan, applicable regulator.
In this role, the selected candidate will facilitate customer engagements and directly contribute to the achievement of project deliverables including ad-hoc analyses, reports, structured outputs (such as final study scientific and operational specs), materials for governance bodies, technical reports, presentations, and service dossiers.
In this role, you will be responsible for the interface of the human microbiome, human disease and novel metabolite activity testing for elucidating metabolite mechanism of action in the context of mucosal immunology.
In this role, the selected candidate will utilize the entire suite of protein LC-MS/MS detection systems to develop the most reliable measurements for endogenous proteins critical for derisking pathology and investigative toxicology projects.
The successful candidate will become part of a creative and flexible team that will investigate host/pathogen interactions with the ultimate goal of delivering novel prophylactic or therapeutic interventions to address significant unmet medical need in infectious disease.
In this role, you will explore gene expression changes in disease models, and epigenetic regulation mechanisms at high resolution in the central nervous system using cutting edge sequencing technologies.
In this role, you will be responsible for coordinating recruitment and follow-up, managing daily operations, serving as a liaison/resource to the local and out of state project teams/individuals, initiates monthly conference calls, monitors project compliance, training,budgeting, prepares grant-related reports and maintains local irb requirements.
In this role, the selected candidate will participate in all phases of flow laboratory operations including new technology evaluations, the development of sample preparation and detection methods, data analysis, QC, data reporting and follow up discussions with the project teams for data integration and appropriate decision making.