The successful applicant will interface with domain area experts in computational sciences, medicinal chemistry, structural biology, analytical chemistry, PDM and primary pharmacology groups and will be accountable for developing and delivering computational solutions for key medicine design project team endpoints.
As a Senior Scientist - Protein Crystallography, you will apply expert knowledge to determine the atomic structures of novel drug target proteins and protein-ligand complexes by protein crystallographic methods and extract novel and relevant structural insights to drive drug discovery efforts.
A Senior Scientist (level R4) position is available in the Purification Process Development group, Bioprocess R&D. The successful applicant will have experience in laboratory research, and a desire to continue in a laboratory-focused role.
This laboratory scientist will provide high quality in vitro plate-based pharmacology data to project teams to enable rapid decision making in support of the Worldwide Research and Development portfolio.
In this role, you will contribute to the clinical oversight and medical guidance in collaboration with the Principal Clinical Scientist and (Senior) Global Clinical Program Director during the conduct of the study.
The Senior Clinical Research Associate demonstrates superior monitoring skills and ensures that study recruitment and data quality targets are met at the site level for 15-20 sites with multiple protocols.
The Senior Scientist will be part of the Biopharmaceutics Group and will provide guidance and recommendations on biopharmaceutics aspects for drug products during their entire lifecycle from early development to post marketing changes.
The successful candidate will enable and develop scalable processes to pharmaceutical drug candidates which are safe, efficient and robust through thoughtful experimentation in a laboratory setting. The ability to work on multi-disciplinary teams involving chemists, analysts, engineers, and technologists is essential.
This scientist will act as a technical and scientific lead for assay development and clinical sample processing, advance innovation in new biomarker technologies, and contribute to developing strategies for high content data visualization and analysis.
Incumbent will be responsible for the development and qualification of novel, multi-color flow cytometry assays in support of various Pfizer vaccine programs from vaccine discovery through clinical development.
In this role, you will work cross functionally with the Marketing and Sales teams to determine market needs within the industry and assists in identification of innovative solutions in order to meet those needs.
The successful candidate will be responsible for designing and executing experiments as well as developing LC-MS based methods. Approaches include, but are not limited to proteomics, phopospoproteomics, interaction proteomics, and chemoproteomics studies.
In this role, the selected candidate will own and drive the customer planning and design engagements, including program management of the Structured Design methodology enabled by Infosario Design and other advanced technologies.
The successful candidate will collaborate with study teams working effectively to design studies, develop protocols, write statistical analysis plans, perform statistical analysis, write reports, present results summarizing findings, and develop publications of results.
As a senior scientist in the Discovery Chemistry Separations group you will work with our team developing analytical chromatographic methods and performing challenging preparative separations of complex mixtures using a variety of chromatographic and analytical technologies.
The laboratory role will provide expertise and laboratory support for discovery and quantification of safety protein biomarkers including the development of targeted chemoproteomics capabilities using chemical probes.
In this role, the selected candidate will manage multiple projects within Bioanalytical Operations (BAO). Work closely with groups within BAO, clinical teams and other working groups to establish project objectives and ensure they are achieved to support clinical development.