In this role, you will explore gene expression changes in disease models, and epigenetic regulation mechanisms at high resolution in the central nervous system using cutting edge sequencing technologies.
In this role, you will serve as the operations point of contact for technology transfer and start-up of products by reviewing process parameter tables, site assessments, review and approve plant documentation, change controls, process overview presentations, sampling plans, and other tech transfer deliverables.
In this role, the selected candidate will utilize the entire suite of protein LC-MS/MS detection systems to develop the most reliable measurements for endogenous proteins critical for derisking pathology and investigative toxicology projects.
As a Research Associate within the group, your responsibilities will include, but not be limited to, making targeting vectors to modify mouse embryonic stem cell, working closely with other scientists to support projects as they progress through the pipeline, developing and optimizing new technologies.
In this role, the selected candidate will contribute routine scientific knowledge or expertise to research and development activities for achievement of project goals and solve routine experimental design or research problems with some assistance.
In this role, you will be responsible for
expression, purification, characterization, crystallization, structure determination and biophysical characterization of proteins and protein-ligand complexes.
In this role, the selected candidate will participate in all phases of flow laboratory operations including new technology evaluations, the development of sample preparation and detection methods, data analysis, QC, data reporting and follow up discussions with the project teams for data integration and appropriate decision making.
In this role, the selected candidate will develop applications notes and validated protocols using a portable GCMS based technology; write copy to support applications data and leads the review of papers with key stakeholders.
In this role, the selected candidate will contribute to the development and optimization of knowledge base intranet resources and facilitate archiving, sharing and leveraging of development program review information.
In this role, the selected candidate will design, develop and validate immunoassays using ELISA, MSD or Gyros platforms for pharmacokinetic (PK), anti-drug antibodies (ADA) or biomarker detection in serum or plasma to support clinical or non-clinial bioanalysis.