This position is required to plan, lead and/or execute studies towards formulation development for preclinical and clinical stage molecules. The incumbent will also serve in the capacity of formulation subject matter expert for formulation-related matters across Alexions commercial, clinical and preclinical stage products.
Manage and implement medical research activities and coordinates strategies essential to the successful administration of research projects; carry out translational research for development of disease-related biomarkers.
Scientist III, you will be responsible for conducting mechanistic in vitro studies to evaluate metabolic and transporter interactions of drugs and experimental compounds in various in vitro models including but not limited to hepatocytes.
The Distinguished Research Fellow, Cancer Immunology Biomarkers, will lead a team that is responsible for identification and validation of candidate molecular biomarkers used for demonstration of PD effects and MoA, as well as for response prediction and patient selection/stratification.
In this role, the selected candidate will be able to work with raw data, experienced in interpreting and dealing with outliers and missing values. Able to browse and understand the actual companies quarterly and annual filings (SEC forms 10-Q and 10-K).
The scientist will work closely with his/her supervisor to conduct routine in vitro drug metabolism studies designed to evaluate small molecules as inhibitors of drug metabolizing enzyme. Additionally this individual will be responsible for routine administrative tasks.
The analyst will take on special IR&D and Government Finance-related projects as required. These will provide unique opportunities to interact with contacts throughout Finance as well as Engineering, Program Management, Contracts and Legal, often including interaction with Senior and Executive Management. These projects may involve, but are not limited to: litigation avoidance and support, strategic/long-term financial planning, and proactive cost accounting problem/issue avoidance.